Set in the near future, Senritsu no Stratas is a battlefield where humans fight an invisible enemy. The Meems are monsters that usurp information and use them to possess the humans. To counter this menace, Imperial City Tokyo set up an agency, led by Takanosu Misogi. Everyone in the team have been partly possessed and proves to be able to use what the Meems gave them as a weapon against the Meems.
The ace of the team is Kudan Seishiro, who is drafted by force. His sister died because of inappropriate governmental measures and his grudge and distrust might become his team and mankind’s undoing.